Original Research

Immunotherapy for Treatment of Resistant Cancer

A. Chota, W. Kruger, J.A. Pienaar
The Journal of Medical Laboratory Science & Technology of South Africa | Vol 1, No 4 | a109 | DOI: https://doi.org/10.4102/jmlstsa.v1i4.109 | © 2019 A. Chota, W. Kruger, J.A. Pienaar | This work is licensed under Other
Submitted: 15 January 2026 | Published: 15 November 2019

About the author(s)

A. Chota, Department of Biomedical Technology, University of Johannesburg, South Africa
W. Kruger, Department of Biomedical Technology, University of Johannesburg, South Africa
J.A. Pienaar, Department of Biomedical Technology, University of Johannesburg, South Africa

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Abstract

Background: Cancer is the leading cause of mortality in developed countries and second cause of disease in developing countries. The aetiology of cancer resistance is prolonged exposure to carcinogenic agents and adaptation of cancer associated lifestyles, such as: smoking, diet, alcohol, sun exposure, and environmental to name just a few.
Objective: This literature review aimed to highlight different immunotherapeutic approaches in the treatment and management of resistant cancer.
Method: A literature review of pertinent literature was conducted to ascertain the effectiveness of immunotherapy in resistant cancer. Google Scholar, PubMed and research gate were used to obtained related journal articles.
Results: Immunotherapy has proven to be the best therapeutic approach to be applied in the treatment of resistant cancer as it induces the immune system to produce specific antibodies to cancer surface antigens.
Conclusion: Immunotherapy is the best therapeutic approach to be employed in treatment and management of resistant cancer.

Keywords

immunotherapy; monoclonal antibodies; therapeutic strategies; resistant cancer; CRISPR application; biotherapy

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